LECTURE III    DEMENTIA PRAECOX (INSANITY OF ADOLESCENCE)

        GENTLEMEN,You have before you to-day a strongly-built and well-nourished man, aged twenty-one, who entered the hospital a few weeks ago.  He sits quietly looking in front of him, and does not raise his eyes when he is spoken to, but evidentlv understands all our questions very well, for he answers quite relevantly,though slowly and often only after repeaeed questioning.  From his brief remarks, made in a low tone, we gather that he thinks he is ill, without getting any more precise information about the nature of the illness and its symptoms.  The patient attributes his malady to the onanism he has practised since he was ten years old.  He thinks that he has thus incurred the guilt of a sin against the sixth commandment, has very much reduced his power of working, has made himself feel languid and miserable, and has become a hypochondriac.  Thus, as the result of reading certain books, he imagined that he had a rupture and suffered from wasting of the spinal cord, neither of which was the case. He would not associate with his comrades any longer, because he thought they saw the results of his vice and made fun of him. The patient makes all these statements in an indifferent tone, without looking up or troubling about his surroundings.  His expression betrays no emotion; he only laughs for a moment now and then. There is occasional wrinkiing of the forehead or facial spasm.   Round the mouth and nose a fine,  changing twitching is constantly observed.
          The patient gives us a correct account of his past experiences. His knowledge speaks for the high degree of his education; indeed, he was ready to enter the University a year ago.  He also knows where he is and how long he has been here, but he is only very imperfectly acquainted with the names of the people round him, and says that he has never asked about them.  He can only give a very meagre account of the general events of the last year.   In answer to our questions, he declares that he is ready to remain in the hospital for the present.  He would certainly prefer it if he could enter a profession, but he cannot say what he would like to take up.  No physical disturbances can be definitely made out, except exaggerated knee-jerks.
         At first sight, perhaps, the patient reminds you of the states of depression which we have learned to recognise in former lectures.  But on closer examination you will easily understand that, in spite of certain isolated points of resemblance, we have to deal here with a disease having features of quite another kind. The patient makes his statements slowly and in monosyllables, not because his wish to answer meets with overpowering hindrances, but because he feels no desire to speak at all.  He certainly hears and understands what is said to him yery well,but he does not take the trouble to attend to it.  He pays no heed, and answers whatever occurs to him without thinking. No visible effort of the will is to be noticed. All his movements are languid and expressionless, but are made without hindrance or trouble.  There is no sign of emotional dejection, such as one would expect from the nature of his talk, and the patient remains quite dull throughout, experiencing neither fear nor hope nor desires.  He is not at all deeply affected by what goes on before him, although he understands it without actual difficulty.  It is all the same to him who appears or disappears where he is, or who talks to him and takes care of him, and he does not even once ask their names.
           This peculiar and fundamental want of any strong feeling of the impressions of life, with unimpaired ability to understand and to remember, is really the diagnostic symptom of the disease we have before us.  It becomes still plainer if we observe the patient for a time, and see that, in spite of his good education, he lies in bed for weeks and months, or sits about without feeling the slightest need of occupation.  He broods, staring in front of him with expressionless features, over which a vacant smile occasionally plays, or at the best turns over the leaves of a book for a moment, apparently speechless, and not troubling about anything.  Even when he has visitors, he sits without showing any interest, does not ask about what is happening at home, hardly even greets his parents, and goes back indifferently to the ward.  He can hardly be induced to write a letter, and says that he has nothing to write about.  But he occasionally composes a letter to the doctor, expressing all kinds of distorted, half-formed ideas, with a peculiar and silly play on words, in very fair style, but with little connection.  He begs for 'a little more allegro in the treatment,' and 'liberationary movement with a view to the widening of the horizon,' will ' ergo extort some wit in lectures,' and 'nota bene for God's sake only does not wish to be combined with the club of the harmless.'  'Professional work is the balm of life.' These scraps of writing, as well as his statements that he is pondering over the world or putting himself together a moral philosophy, leave no doubt that, besides the emotional barrenness, tbere is also a high degree of weakness of judgment and flightiness, although the pure memory has suffered little, if at all. We have  a mental and emotional infirmity  to deal with,  which reminds us only outwardly of the states of depression previously described.  This infirmity is the incurable outcome of a very common history of disease, to which we will provisionally give the name of Dementia Praecox.
        The development of the illness has been quite gradual.  Our patient, whose parents suffered transitorily from 'dejection,' did not go to school till he was seven years old, as he was a delicate child and spoke badly, but when he did he learned quite well. He was considered to be a reserved and stubborn child.  Having practised onanism at a very early age, he became more and more solitary in the last few years, and thought that he was laughed at by his brothers and sisters, and shut out from society because   of   his    ugliness.               For    this    reason    he    could    not    bear    a    looking-glass in his room.  After passing the written examination on leaving school, a year ago, he gave up the viva voce, because he could not work any longer.  He cried a great deal, masturbated much, ran about aimlessly, played in a senseless way on the piano, and began to write observations 'On the Nerve-play of Life,' which he cannot get on with.'  He was incapable of any kind of work, even physical, felt 'done for,' asked for a revolver, ate Swedish matches to destroy himself, and lost all affection for his family. From time to time he became excited and troublesome, and  shouted out of the window at night.  In the hospital, too, a state of excitement lasting for several days was observed, in which he chattered in a confused way, made faces, ran about at full speed, wrote disconnected scraps of composition, and crossed and recrossed them with flourishes and unmeaning combinations of letters.  After this a state of tranquillity ensued, in which he could give absolutely no account of his extraordinary behaviour.[ The patient afterwards returned to the care of his family unchanged.]
         Besides the mental and emotional imbecility, we meet with other very significant features in the case before us.  The first of these is the silly, vacant laugh, which is constantly observed in dementia praecox.  There is no joyous humour corresponding to this laugh; indeed, some patients complain that they cannot help iaughing, without feeling at all inclined to laugh.  Other important symptoms are mahing faces or grimacing, and the fine muscular twitching in the face which is also very characteristic
of  dementja praecox.  Then we must notice the tendency to peculiar, distorted turns of speech--senseless playing with syllables and words--as it often assumes very extraordinary forms in this disease.  Lastly, I may call your attention to the fact that, when you offer him your hand, the patient does not grasp it, but only stretches his own hand out stiffly to meet it.  Here we have the first sign of a disturhance which is often developed in dementia praecox in the most astounding way.
          As the illness developed quite gradually, it is hardly possible to fix on any particular point of time as the beginning.  In such cases, the change which is taking place is easily referred to some culpable looseness of morality, which it is sought to combat by educational means.  Onanism in particular,  which  is very common in our patients, is usually held to be the source of the disease, so that cases of this kind were formerly spoken of as the insanity of onanism.  I am nevertheless inclined to see in onanism a symptom, rather than the cause, of the disease.  We often see the whole severe mental and physical condition arise, without any striking degree of onanism, and we also know degenerate onanists who present quite different symptoms.  Hence there cannot well be any question of a regular causal connection between onanism and dementia praecox.  Besides, the disease is just as common among women, in whom the weakening effect of onanism must be much slighter.  Lastly, it is to be observed that the disease often sets in quite suddenly, another circumstance not exactly adapted to confirm the supposition of its onanistic origin [Kraepelin, 1968, 21-4].
 

Bibliography of Kraepelin's works.
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Eugen Bleuler [1857-1939] introduced the term Schizophrenia into psychiatry.
               He was born in a suburb of Zurich, Switzerland. After finishing his medical training he took a position as a resident at the Waldau mental hospital near Bern. He left there to study with Charcot and Magnan in Paris, to travel to London and Munich and then join the staff of the Burghölzi Mental Hospital, which was then directed by August Forel [1848-1041].
            In 1886, Bleuler was appointed medical director of the Rheinau mental hospital. For the next twelve years he lived closely with his patients, spoke their dialect and made every effort to understand their 'senseless' utterings and delusions. In 1898 he succeeded Forel as the director of the Burghölzi.
             Bleuler was the personification of work and duty. He demanded a strenuous amount of work and devotion to patients. Abstinence from alcohol was imposed on everyone. Among his staff, after 1900, was Carl Gustav Jung. Although Jung does not mention Bleuler in his autobiography and says that 'the psychology of the mental patient played no role whatsoever' at the Burghölzi, this is unanimously contradicted by everyone else who worked with Bleuler [Ellenberger, 1970, 666-7.
            Bleuler was favorably impressed by Freud and asked Jung to report on Freud's Interpretation of Dreams to the Burghölzi staff in 1906. for a brief time Bleuler became a member of the budding psychoanalytic organization. He attended its 1908 international congress and founded, with Freud, the Jarbuch für psychoanalytische und psychopathologische Forschung [Yearbook for Psychoanalytic and Psychopathological Research], with Jung as editor. Bleuler wrote a small volume in defense of Freud's psychoanalysis, which appeared in 1911, by which time Bleuler had already parted company with the movement on the basis of what he considered to be Freud's excessive emphasis on infantile sexuality [Stone, 1997, 147].
           In 1911 Bleuler published book  Dementia Praecox or the Group of Schizophrenias. The title of the book reflected the fact that Bleuler did not like the term Dementia Praecox. He felt that it was misleading both because it implied deterioration, which he did not think was inevitable, and because it suggested the presence of a true dementia like senile dementia, which was not the case. Nonetheless Bleuler and Kraepelin had the same case material in mind and Bleuler  never intended to oppose Kraepelin's views.
         Kraepelin's view  at first did not find much acceptance outside the circle of his co-workers, and in fact encountered much resistance. This did not change until the appearance of Eugen Bleuler's book . This book, and the greatly enlarged 8th edition of Kraepelin's textbook in 1913 broke the deadlock and brought general acceptance not just in Germany but in the world--except in France [Hoenig, 1995, 342].
         Kraepelin's Dementia Praecox and Bleuler's schizophrenia, however, differ in more than the implications of their names.  Kraepelin's Dementia Praecox always included psychotic symptoms, Bleuler's Schizophrenia did not. Kraepelin's approach is purely observational and empirical. He avoids any kind of theorizing about his observations.
 Bleuler is guided by the theory that an unknown cerebral disease process expresses itself through primary or fundamental symptoms, often referred to as the four A's: altered associations, altered affectivity, ambivalence and autism. Bleuler insisted that 'once the schizophrenic anomalies of association have been proven, the diagnosis is assured [Bleuler, 1911,283].  The secondary symptoms such as hallucinations and delusions were not due to the disease process, but to life experiences.
         Ellenberger has suggested that this distinction was probably inspired by Pierre Janet's concept of psychasthenia, which has a primary physiological process of lowered psychological tension and a secondary elaboration of specific symptoms. For Bleuler the primary symptoms of schizophrenia were due to a loosening of the tension of associations, as occurs in dreams [Ellenberger, 1970, 287].
           Kraepelin insisted that Dementia Praecox was a single disease, even though he thought that no single symptom occurred in every case. Bleuler identified primary symptoms, which he felt occurred in every case, yet he spoke about the 'Group of Schizophrenias.' Bleuler's expanded notion of schizophrenia led to the creation of subtypes. Simple schizophrenia, for example, could be diagnosed in patients who showed only the fundamental symptoms. Bleuler argued that there are people who have 'the disease' while having no schizophrenic symptoms, not even the fundamental ones.  These he regarded as having 'latent schizophrenia,' which he believed was  'the most frequent occurring form even though it comes under treatment the least often.' [Hoenig, 1995,341-2]
          While in recent years Bleuler's definition of Schizophrenia has been regarded as too broad to be useful for classification, its inclusiveness did encourage therapeutic optimism. Because Bleuler thought that Schizophrenia could be stopped or reversed at any stage, he made an active effort to treat his patients. He would resort to early discharge of apparently severely ill patients, or to unexpected transfers to another ward. He organized a system of work therapy and arranged for leisure time activities for has patients [Ellenberger, 1970,288].
 

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'Dear Mother: Today I am feeling better than yesterday. I really don't feel much like writing. But I love to write to you. After all, I can tackle it twice. Yesterday, Sunday I  would have been so happy if you and Louise and I could have gone to the park. One has such a lovely view from Stephan's Castle. Actually, it is very lovely in Burgholzli. Souise wrote Burgholzi on her last two letters, i mean to say on the envelopes, no, the 'couverts' which I received. However, I have written Burgholzi on the spot where I put the date. There are also patients in Burgholzi who call it 'Holzliburg.' Others talk of a factory. One may also regard it as a health-resort.
      'I am writing on paper. The pen which I am using is from a factory called 'Perry & Co.' This factory is in England. I assume this. Behing the name of Perry Co. the city of London is inscribed; but not the city. The city of London is in England. I know this from my school-days. Then, i always liked geography. My last teacher in that subject was Professor August A. He was a man with black eyes. I also liked black eyes. There are also blue and gray eyes and other sorts, too. I have heard it said that snakes have green eyes. All people have eyes. There are some, too, who are blind. These blind people are led about by a boy. It must be terrible not to be able to see. There are people who can't see and, in addition, can't hear. I know some who hear too much. One can hear too much. There are many sick people in Burgholzli; they are called patients. One of the I like a great deal. His name is E. Sch. He taught me that in Burgholzli there are many kinds, patients, inmates, attendants. Then there are some who are not here at all. They are all peculiar people...'

     About this example Bleuler comments: 'A non-schizophrenic informant would tell us what  in his immediate invironment affected him; what may have made him feel comfortable or uncomfortable; or, perhaps, something that might interest his reader. There is complete absence of any such purpose here. The common denominator of all of the patient's ideas rests in the fact that they are present in his awareness, but not because they have any close relation to him. ... Although nearly all the ideas expressed are correct, nevertheless the letter is meaningless. The patient has the goal of writing, but nothing to write about [Bleuler, 1911/1950, 17-8].'
 

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