Kittichai Promrat, M.D.

Assistant Professor of Medicine

Address:

Gastroenterology Section
Providence VA Medical Center
830 Chalkstone Avenue
Providence, RI 02908
phone: 401-273-7100 ext 3456
fax: 401-457-3364
E-mail:Kittichai_Promrat@Brown.edu

Research and Clinical Interests:

I am interested in the natural history and therapy of chronic liver diseases, in particular hepatitis B, C and nonalcoholic steatohepatitis (NASH). My research efforts involve the roles of insulin resistance and obesity in the pathogenesis of NASH. Another area of research interest is in identification of host immunogenetic factors that involve in clinical outcomes and treatment responses of viral hepatitis.

Selected Publications:

Lee P, Promrat K, Mallette C, Flynn M, Beutler E. A juvenile hemochromatosis patient homozygous for a novel deletion of cDNA nucleotide 81 of hemojuvelin. Acta Haematol. 2006;115(1-2):123-7.

Promrat K, Wands JR.  Aetiology of fulminant hepatitis.  In:  Viral Hepatitis, 3rd Edition.  Thomas H, Zuckerman A, Lemon S (eds).  England:Blackwell Publishing 2005;651-65.

Promrat K, Lutchman G, Uwaifo GI, Freedman RJ, Soza A, Heller T, Doo E, Ghany M, Premkumar A, Park Y, Liang TJ, Yanovski JA, Kleiner DE, Hoofnagle JH. A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology. 2004 Jan; 39(1): 188-96.

Promrat K, Liang TJ. Chemokine systems and hepatitis C virus infection: is truth in the genes of the beholders? Hepatology. 2003 Dec;38(6):1359-62.

Hoofnagle JH, Ghany MG, Kleiner DE, Doo E, Heller T, Promrat K, Ong J, Khokhar F, Soza A, Herion D, Park Y, Everhart JE, Liang TJ. Maintenance therapy with ribavirin in patients with chronic hepatitis C who fail to respond to combination therapy with interferon alfa and ribavirin. Hepatology. 2003 Jul;38(1):66-74.

Promrat K, McDermott DH, Gonzalez CM, Kleiner DE, Koziol DE, Lessie M, Merrell M, Soza A, Heller T, Ghany M, Park Y, Alter HJ, Hoofnagle JH, Murphy PM, Liang TJ. Associations of chemokine system polymorphisms with clinical outcomes and treatment responses of chronic hepatitis C. Gastroenterology. 2003 Feb;124(2):352-60. Erratum in: Gastroenterology. 2003 Apr;124(4):1168.

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