Director, Clinical Molecular Biology Laboratory
Associate Professor of Pathology
Cynthia_Jackson@Brown.edu
T: 401 444-4370
F: 401 444-8514
Rhode Island Hospital
Department of Pathology
APC 12-121
593 Eddy Street
Providence, RI 02903
Medical education/Graduate education:
Ph.D. University of Illinois, Urbana, Biochemistry, 1983
Fellowship:
Postdoctoral Research Fellow, Children’s Hospital Medical Center, Harvard Medical School, Boston, MA 1983-1984
Postdoctoral Research Fellow, Center for Cancer Research, Mass. Institute of Technology, Cambridge, MA 1984-1988
Research interests:
Tumor suppressor genes, Cartilage hair hypoplasia
Current approved research grants:
“Identification of a gene located at chromosome 9p13: Important in adenoid cystic carcinoma. National Organization of Rare Diseases. April 1, 2001 – March 31, 2002. The goal of this project is to characterize adenocystic tumors for alterations in 9p13 and evaluate potential tumor suppressor genes for a role in this tumor.
“Evaluation of GPR30, a novel estrogen receptor for assessing responsiveness to anti estrogen therapy. US Department of Defense Young Investigator Award; July 1, 2000 – June 30, 2004. assist in the molecular analysis at GPR30.
Production of a Mouse Model for Cartilage-Hair hypoplasia. Principal investigator: NIH NIAMS. R21 Period September 1, 2002- August 31, 2004. This grant is to produce a knockout mouse and a cartilage specific knockout mouse for RMRP, the causative gene.
Most recent significant publications:
Bearer E, Chen AH, Chen AF, Li Z, Smith RJ, Mark HFL and Jackson CL. (2000). 2E4/Kaptin, a candidate gene for the deafness locus, DFNA4. Annals of Human Genetics 64:288-296.
Mills DR, Jackson, CL. (2001). Assignment1 of p22 dynactin light chain (DCTN3) to human region 9p13 by radiation hybrid mapping. Cytogenetics and Cell Genetic 92(1-2):166.
Prakash P, Manfredi TG, Jackson CL and Gerber LE. (2002). Beta-carotene alters the morphology of NCI-H69 small cell lung cancer cells. Journal of Nutrition 132: 121-124.
