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Research into
Twin-to-twin Transfusion Syndrome
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Face (above) and
hand of a 20-week-old fetus, as seen through the lens of a fetal
endoscope during surgery for Twin-to-twin Transfusion Syndrome
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Our center is actively involved
in medical research, including research into the causes and the
treatment of twin-to-twin transfusion syndrome. Research interests
include the fine-tuning of actual surgical techniques and examining
the placental vessels
after delivery to better understand the causes of TTTS. Below
is a list of recent publications on the topic - for a more comprehensive
list of scientific publications from the Program in Fetal Medicine
at Brown Medical School, click
here.
Carr SR, Plevyak MP.
Contemporary evaluation and management of twin-twin
transfusion syndrome.
Med Health RI 2001;84:165-168.
Luks FI, Carr SR, Ponte B, Rogg
JM, Tracy TF, Jr.
Preoperative planning with magnetic resonance imaging
and computerized volume rendering in twin-to-twin transfusion
syndrome.
Am
J Obstet Gynecol 185:216-219, 2001.
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Fig. 1. A 29-week diamniotic–monochorionic
placenta before (left) and after (right) vascular injection.
Color code: yellow, artery twin A; blue, vein twin A; red, artery
twin B; green, vein twin B. Arteries are seen crossing over veins.
Inset shows a deep artery-to-vein (AV) anastomosis between yellow
artery of twin A and green vein of twin B (direction: A3B). De
Paepe ME, et al.
Pediatr Dev Pathol 5, 37–44, 2002 © 2002 Society for
Pediatric Pathology |
De Paepe ME, Burke S, Luks FI,
Pinar H, Singer DB.
Demonstration of placental vascular anatomy in
monochorionic twin gestations.
Pediatr Dev Pathol 5:37-44, 2002.
De Paepe ME, Stopa E, Huang C, Hansen K, Luks FI.
Renal tubular apoptosis
in twin-to-twin transfusion syndrome.
Pediatr Dev Pathol 6:215-225, 2003.
Luks FI, Carr SR, Feit LR, Rubin
LP.
Experience
with a Multidiscipinary Antenatal Diagnosis And Management model
in fetal medicine.
J Mat Fet Neonat Med 14:333-337, 2003.
Bussey JG, III, Luks FI, Carr SR, Plevyak M, Tracy TF, Jr.
Minimal access fetal
surgery for twin-to-twin transfusion syndrome (TTTS).
Surg Endosc 18:83-86,
2004.
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