150
sample questions, and note trouble areas to
focus on.
3
hrs
General
overview of material to be covered
Read
Through Section Introductory Material from
First Aid, and Skim Section II
First
Aid
Learn
about the test, and how to best use First
Aid as a resource.
4
hrs
Basic
Metabolism
Chapters
5 & 6, and sample questions at end of
each chapter. Bookmark
figure 6.2 and refer to it before studying
each biochemical pathway.
Lippincott's
Biochemistry
Understand
the role of ATP. Know where the electron transport
chain, and oxidative phosphorylation occur
and how they fit into the overall metabolic
scheme. Review the main classes of cell receptors
and signalling mechanisms.
2.5
hrs
Day
2
Continue
Biochemistry
Objective
Assignments
Source
Details
Est.
Time
Structure
& Metabolism of Carbohydrates
Chapters
11, 12, 13 & questions
Lippincott's
Biochemistry
Review
the digestion of sugars and disorders of fructose,
galactose, and lactose metabolism. Spend more
time on glycogen metabolism, its regulation,
and related disorders. Use Figure 13.7 to
memorize the glycogen storage diseases.
3
hrs
Glycolysis
Chapter
7 & questions
Lippincott's
Biochemistry
Know
the start and end points, hormonal regulation,
energy yield, and various fates of pyruvate.
1.5
hrs
Gluconeogenesis
Chapter
8 & questions, Review
Figure 6.2 again!
Lippincott's
Biochemistry
Study
it by comparison to glycolysis. Know the reactions
& regulation unique to gluconeogenesis.
1
hr
Citric
Acid Cycle
Chapter
9 & questions
Lippincott's
Biochemistry
Focus
on start and end points, place in overall
metabolism, and regulation.
1
hr
Hexose
Monophosphate Shunt
Chapter
10 & questions
Lippincott's
Biochemistry
Skim
reactions and focus on G6PD deficiency.
1
hr
Day
3
Continue
Biochemistry
Objective
Assignments
Source
Details
Est.
Time
Lipid
Metabolism
Chapter
17 & questions
Lippincott's
Biochemistry
Focus
on roles of pancreatic lipase and bile salts.
Fatty acid metabolism: know where synthesis
occurs, relationship to glucose metabolism,
and role of triacylglycerols for storage of
fatty acids. Review mobilization of and oxidation
of fatty acids. Finally, carefully review
eicosanoids, focusing on figure 17.20
3
hrs
Phospholipids
& Glycolipids
Skim
Chapters 18, 19
Lippincott's
Biochemistry
Gain
a sense of what these are, but do not memorize
structures or pathways. Focus on related disorders
instead, using figures 18.10, 19.4.
1
hr
Cholesterol
& Steroid Metabolism
Chapter
20, Sect. I-VII
Lippincott's
Biochemistry
Review
cholesterol synthesis (esp. the role of HMG
CoA reductase) and its regulation. Understand
synthesis and role of bile salts. Review biology
of lipoproteins and their role in atherogenesis.
Key figures are 20.12, 20.14, 20.16.
2
hrs
Steroid
Hormones
Chapter
20, Sect. VII
Lippincott's
Biochemistry
Know
the major enzyme deficiencies in steroid synthesis
and know where steroid receptors act in the
cell. Study figures 20.19, 20.20.
1
hr
Day
4
Continue
Biochemistry
Objective
Assignments
Source
Details
Est.
Time
Protein
& Enzymes
Chapters
1-4 & questions
Lippincott's
Biochemistry
Become
familiar with basic properties of amino acids,
levels of protein structure, hemoglobin, and
collagen. For enzymes, focus on appreciating
( not memorizing) the Michaelis-Menten equation,
types of enzyme inhibition, modes of enzyme
regulation, and the use of enzymes in clinical
diagnosis.
4
hrs
Digestion
of Dietary Proteins and Nitrogen Metabolism
Chapter
21 & questions
Lippincott's
Biochemistry
Learn
the various pancreatic proteases and how they
are regulated. Understand transamination and
oxidative deamination, but don't memorize
pathways. Spend more time on urea cycle and
ammonia metabolism focusing on figures 21.4,
21.11, 21.17.
2
hrs
Metabolism
of Amino Acid Carbon Skeletons
Chapter
22
Lippincott's
Biochemistry
Emphasize
relevant disorders. Focus on figures 22.2,
22.16.
1
hr
Day
5
Continue
Biochemistry
Objective
Assignments
Source
Details
Est.
Time
Heme,
Porphyrins, Serotonin, Histamine and Catecholamines
Chapter
23
Lippincott's
Biochemistry
Focus
on the porphyrias and bilirubin metabolism.
Focus on figures 23.5 and 23.7.
1
hr
Glycosaminoglycans
and Glycoproteins
Skim
Chapters 14, 15
Lippincott's
Biochemistry
Know
what they are and know the related disorders.
Don't get too bogged down in details - just
study figures 14.12 and 15.4, then move on.
1
hr
Nutrition
and Vitamins
Chapters
27, 28
Lippincott's
Biochemistry
Know
the daily energy requirements and vitamin
deficiences. Focus on absorption of vitamin
B12 and pernicious anemia, as well as vitamin
D. Focus on figures 28.12, and 28.18.
3
hrs
Nucleotide
Metabolism
Chapter
29
Lippincott's
Biochemistry
Understand
differences between de novo and salvage purine
synthesis. Study purine degradation and the
pathophysiology of gout and ADA deficiency.
Study figures 29.7, 29.9, 29.10.
2
hrs
Day
6
Finish
Biochemistry
Objective
Assignments
Source
Details
Est.
Time
Integrative
Metabolism
Chapters
24, 25, 26
Lippincott's
Biochemistry
Synthesize
the information you've reviewed this week
by studying insulin, glucagon, the fed/starved
states, and the metabolic aspects of diabetes
mellitus. Time spent
on these topics will be VERY WORTHWHILE.
5
hrs
Day
7
General
Pharmacology
Objective
Assignments
Source
Details
Est.
Time
Pharmacokinetics
& Pharmacodynamics
Chapters
1,2
Lippincott's
Pharmacology
Study
general principles of pharmacology. Specific
agents will be covered with relevant organ
systems.
2
hrs
Autonomic
Drugs
Chapters
3-7
Lippincott's
Pharmacology
Know
different types of adrenergic and cholinergic
receptors cold.
Study figures 3.3, 3.6, 4.2, 5.2, 6.15, 7.10.
5
hrs
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