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Transplant Services
Department of Surgery
Brown University School of Medicine
FACULTY
Anthony Monaco
Mass. General Hospital, Harvard Medical School
Professor of Surgery, Beth Israel-Deaconess Medical Center
Peter Madras
Boston City Hospital, Harvard Medical School - Toronto General [fellow]
Associate Prof. Surgery, BIDMC
Paul Morrissey
Yale-New Haven Hospital, Yale School of Medicine
Asst. Prof. of Surgery, Brown University School of Medicine
Reginald Gohh
Rhode Island Hospital
Asst. Prof. of Medicine, Brown University School of Medicine
RESEARCH PROGRAMS
Anthony Monaco, MD
Transplant Tolerance through Donor Stem Cell Infusion. Clinical study of infusions
of donor stem cells after renal transplantation.
Steroid withdrawal after Simulect Induction in Renal Transplant. Multi-center trial of mAb to IL-2 Receptor.
Reginald Gohh, MD
Hepatocyte Growth Factor following Nephrectomy and Renal Transplantation. Evaluation
of HGF following donor nephrectomy and ischemia-reperfusion injury.
Andy Bostom, MD, Reginald Gohh, MD
Effect of Vitamin Therapy on Plasma Homocysteine levels in Renal transplant
Patients.
CLINICAL PROGRAMS
Renal transplantation was introduced to Rhode Island Hospital in 1996, and the first transplant was performed in March of 1997. Thirty-five transplants were performed that year and we are on pace to perform 45 renal transplants in 1998. In 1999, we hope to expand the program to include pancreas transplantation and a liver transplant clinic to be operated in conjunction with our Lifespan colleagues at the New England Medical Center. The program, one of 14 renal transplant programs in New England, is already one of the largest in the region.
The Transplant Clinic at Rhode Island Hospital is a combined Surgical/Medical Clinic that follows more than 400 patients, including 230 after renal transplant, 120 awaiting renal transplant and Vascular Access patients. The integrated effort provides complete medical and surgical care for patients with End Stage Renal Disease, from dialysis through transplantation. The patient base comes from all of Rhode Island and Southeastern Massachusetts. Community education and donor awareness are integrated into the program. Lifelong care and follow-up are provided for the patient through the Rhode Island Hospital Clinic and the patient’s individual nephrologist and/or primary care physician.
EDUCATIONAL PROGRAMS
Monthly Renal Transplant Grand Rounds: These conferences feature frequent guest lecturers and cover a wide variety of topics in transplantation. The entire renal division and residents on the transplant service are invited to attend. Invited speakers in 1998 came from Columbia, University of Maryland, Hennipen County and Vanderbilt.
Weekly Transplant Conference: Renal fellows and Vascular/Transplant residents participate in this conference. Topics include case presentations, lectures on clinical aspects of transplantation, and patient rounds.
Community Service and Outreach Programs: The clinic staff and physicians have participated in several community programs in Transplantation; including lectures at Medical Grand Rounds (Rhode Island Hospital and Miriam), lecture to the Rhode Island Society of Blood Banks, patient support groups, donor awareness programs on local radio (103.7) and cable television (Cox TV), and donor recognition ceremonies.
PUBLICATIONS
Morrissey PE, Gordon F, Shaffer D, Monaco AP, Madras PN, Lewis D and Jenkins RL. Combined liver-kidney transplantation. Liver Transplantation and Surgery 4: 363 — 369, 1998.
Morrissey PE, Gohh R, Madras PN, Shaffer D, Davis C, Conway P, Sahyoun AI and Monaco AP. Etiology of early renal allograft dysfunction after live donor renal transplantation. Transplant Proc 30: 1320, 1998.
Morrissey PE and Monaco AP. A comprehensive approach to organ donation. Hospital Practice 32: 181 - 196, August 15, 1997.
Morrissey PE, Shaffer D, Monaco AP, Conway P and Madras PN. Peripheral vascular complications after kidney-pancreas transplantation versus kidney transplant alone in diabetics with ESRD. Arch Surg 132: 358 - 362, 1997.
Morrissey PE, Gohh R, Shaffer D, Crosson A, Madras PN, Sahyoun A and Monaco AP. Correlation of clinical outcomes after tacrolimus conversion for resistant kidney rejection or cyclosporine toxicity with pathologic staging by the Banff criteria. Transplantation 63: 845 - 848, 1997.
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