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Brown Medical School Division of Surgical Research

Trauma and Inflammation
Research Training Fellowship

Division of Surgical Research, Department of Surgery
Rhode Island Hospital, Lifespan
Brown Medical School

 

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Research Facilities

The Division of Surgical Research at Rhode Island Hospital occupies 16,783 sq.ft. of contiguous space including 11,807 sq. ft. of laboratory space. The remaining space contains offices for the investigators and trainees, conference room/library, and sterilization facility. The Division functions under an “open laboratory” basis with equipment freely shared among investigators. Most laboratories not in the Rhode Island Hospital campus (Principal Investigators: Christine Biron, Ph.D., Agnes Kane, M.D., Ph.D., John Sedivy, Ph.D., James Klinger, M.D. et al.) are located on the Brown Campus and served by a shuttle bus.

Other resources available to the trainees: In addition to the diverse departmental and institutional resources available to the training program through Brown Medical School, the local scientific community, composed of individuals from this center as well as from the VA and Memorial hospitals. This provides trainees access to a truly unique community of scholars. The breadth of informal and formal educational interactions with scientists in these affiliated institutions markedly enhances the opportunities available to trainees.

As a Brown University trainee, participants in the program will also have full access to the core facilities at Brown University as well as those at Rhode Island Hospital. Both institutions are NIH-supported Centers of Biomedical Research Excellence (COBRE). Brown University is a designated COBRE Center for Genetics and Genomics, which includes facilities for the use and analysis of Affymetrix Gene Chip Arrays and the construction of transgenic mice (http://www.brown.edu/Research/Genetics_Genomics).

Rhode Island Hospital is also a COBRE Center for Proteomics and Molecular Pathology (PI: Douglas Hixson, Ph.D.) and includes technician-supported facilities for mass spectroscopy, protein chip analysis, HPLC and gel electrophoresis-based proteomics technologies. The Molecular Pathology core facility includes a Stratagene Mx4000 Multiplex Quantitative PCR System for conducting "real-time" PCR, an Arcturus Engineering laser capture microdissection system with microscope and fluorescence capabilities, tissue-array capabilities and a frozen tissue/paraffin-embedded bank of human, mouse and rat tissues.

Rhode Island Hospital maintains a Core Research facility (http://www.lifespan.org/reslab) that includes flow cytometry, scanning and transmission electron microscopy with specimen embedding and sectioning, full histological services including paraffin embedding, sectioning and staining, and inverted and upright confocal microscopes with state-of-the-art image analysis.

Library access is provided by the Rhode Island Hospital and Brown University Science Libraries and by the Brown University on-line electronic library resources.

 

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